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Haynes Lab | ASU

Haynes’ News & Views is published in Nature

Dr. Karmella Haynes’ article discussing Chan et al.’s recent work on genetic containment of genetically modified organisms has been published in Nature Chemical Biology, part of the Nature Publishing Group. Continue reading “Haynes’ News & Views is published in Nature”

Haynes to present at Enzymes in Drug Discovery Summit

Dr. Karmella Haynes will present her latest progress in chromatin protein engineering at the GTCbio “Epigenetic Enzymes in Drug Discovery Summit,” which will take place March 1 – 2, 2016 in San Diego, CA. Continue reading “Haynes to present at Enzymes in Drug Discovery Summit”

Nucleosome cores are screws, not cans or bubbles

Each one of your cells is too small to be seen with the naked eye. Remarkably, each one has 6 feet of DNA packed inside a smaller compartment (nucleus) within the cell. Very complicated data has solved this mystery…can the data be presented in an attractive and understandable way? Continue reading “Nucleosome cores are screws, not cans or bubbles”

New Paper in Biotechnology and Bioengineering

Collaborators from the Haynes Lab (ASU, SBHSE), Rege Lab (ASU, SEMTE), and Elmer Lab (Villanova) published our discovery of how drugs that modify epigenetic mechanisms improve the expression of synthetic genes that are delivered into cultured human cells. Dr. Elmer is the first author. Dr. Haynes and Matt Christensen (Rege Lab) used quantitative PCR to discover that drug treatment led to increased uptake of synthetic DNA into the nuclei of cells. Read the abstract online: http://www.ncbi.nlm.nih.gov/pubmed/26614912.

 

ASU Brings Syn Bio to 5th Graders

On Thursday, October 22, 2016, Haynes Lab PhD student Cassandra Barrett and ASU Professor Michael Caplan presented a hands-on lesson about synthetic biology to a classroom of fifth graders at Phoenix Country Day School. More details to follow.

GMO Labeling: a (chance for) victory for GMO’s

Think of the worst thing that the food industry has done with genetically modified foods (GMOs). If you say “sell them at all,” I’d disagree. I enjoy genetically modified foods, and they rely less on pesticides than “organically” grown foods. More on that later. Continue reading “GMO Labeling: a (chance for) victory for GMO’s”

Professional bullying: personal comments on the recent assault of Dr. Ore

Unfortunately, the disingenuous practice of disguising emotion-driven assaults with a veil of rules and laws is widespread, even amongst esteemed protectors, leaders, and professionals. This is what happened recently when a Tempe Police officer exploited his authority and applied excessive force in apprehending ASU Professor Ersula Ore for jay-walking in an area where the street is currently blocked off and there is no through-traffic on May 20, 2014. Continue reading “Professional bullying: personal comments on the recent assault of Dr. Ore”

Haynes Receives Grant from Women and Philanthropy

Getting a grant is extremely exciting, especially for a young PI who has to find support after she has exhausted her start-up funds. In addition to receiving new funding, something else truly amazing happened. My science-communication skills were challenged like they had never been before. Continue reading “Haynes Receives Grant from Women and Philanthropy”

A Giant Leap for Synthetic Genes

Science magazine has just published the latest tour de force in building genetic machinery from the ground-up since Mycoplasma laboratorium (“Mycoplasma of the laboratory”).

Continue reading “A Giant Leap for Synthetic Genes”

Haynes Lab Students to Present Research at UC Berkeley

Congratulations to the following Haynes Lab students who will present posters at the 2014 Spring Synthetic Biology Engineering Research Center (SynBERC) Retreat on March 24 – 26 at UC Berkeley.

  • Rene Davis (PhD student) – “Investigating quorum sensing orthogonality using a modular, Escherichia coli-based platform” Authors: Rene Davis and Karmella A. Haynes
  • David Barclay (Undergrad, FURI) – “Epigenetic engineering of pancreatic cells with DNA-packing actuators and sensors” Authors: David Barclay, Behzad Damadzadeh, and Karmella A. Haynes
  • Matsemela “Zazu” Moloi (Undergrad, SynBERC Scholars Program) – “Teaching Digital PCR with OpenPCR and a Blue Light Fluorimeter” Authors: Matsemela Moloi, Hiram Rivera-Passapera, Kathryn Scheckel, and Karmella A. Haynes

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