Dr. Haynes to Present CRISPR Research at SERMACS in North Carolina

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Dr. Haynes has been invited to present her group’s latest research on the efficacy of CRISPR editing of human DNA at the 2017 Southeastern Regional Meeting of the ACS (SERMACS) Synthetic Biology Symposium on Thursday, November 9, 2017 in Charlotte, NC. Using a synthetic, regulatable DNA packing system Dr. Haynes and her team, including lead grad student Rene Daer, discovered that chromatin structures similar to those found at stem cell genes can block CRISPR from access to DNA (Daer et al 2017 ACS Synthetic Biology; featured on PRI Science Friday). This can pose a problem for gene therapy and tissue engineering. In her talk “Manipulation of chromatin to enhance CRISPR activity” Dr. Haynes will present a review of these findings as well as recent results from experiments to counteract chromatin and enhance CRISPR activity. The NIH NCI Geographic Management of Cancer Health Disparities Program (GMaP) provided an award to support Dr. Haynes’ travel.

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