Congratulations to Kimberly Olney (PhD, SOLS) who just received a 2018 Achievement Rewards for College Scientists (ARCS) Award. Kimberly is a graduate student who studies genomics and bioinformatics under the mentorship of Dr. Melissa Wilson Sayres, and has collaborated with the Haynes lab to discover genes that are controlled by synthetic chromatin regulators in breast cancer.
Congratulations to Fatima Hamna (Master’s, Biomedical Engineering) who will be joining the Haynes lab this summer with support from the new Master’s Opportunity for Research in Engineering (MORE). She will receive a stipend, materials and supplies, and the opportunity for travel support to present at a research conference.
Haynes lab members Cassandra Barrett and Stefan Tekel will be presenting research at a 2018 Spring Retreat organized by the Engineering Biology Research Consortium (EBRC). The retreat will take place at the University of Washington in Seattle, WA March 23 – 24, 2018. EBRC members include some of the most prestigious labs in synthetic biology. Attendees will come from academic, industry, and government institutions from across the country.
Research – bioRxiv Pre-print – Characterization of Diverse Homoserine Lactone Synthases in Escherichia coli
Characterization of Diverse Homoserine Lactone Synthases in Escherichia coli
Daer R, Barrett CM, Melendez EL, Wu J, Tekel SJ, Xu J, Dennison B, Muller R, Haynes KA. (2018) bioRxiv. https://www.biorxiv.org/content/early/2018/03/09/279349
The Haynes lab focuses on advanced chromosome engineering in human cells, but also provides opportunities for undergraduates to learn synthetic biology using simpler organisms like bacteria (E. coli). In this paper, the 2016 ASU International Genetically Engineered Machines (iGEM) Competition team and their graduate advisors report their work to identify useful, new cell-cell communication components to use in engineered systems. Homoserine lactone (HSL) synthases appear as a wide variety of different forms in the bacterial kingdom, and produce various chemical signals that regulate genes in neighboring bacteria. When these are combined to build synthetic circuits in a common lab strain (E. coli), the signals are sometimes not produced as expected. Therefore, it is important to systematically characterize HSL synthases in context. The team also used experiments to identify the most effective way to neutralize unused HSLs in biological waste. The ten HSL synthases characterized in this paper were contributed to public collections for use by the scientific community.
Jiaqi Wu, a computer science major who is fascinated with computational biology and bioinformatics, has been awarded a prestigious Bidstrup Undergraduate Fellowship for academic year 2017 – 2018. This award is a testament to the outstanding commitment to academic excellence made by Jiaqi and Dr. Haynes as a faculty-student team. Read the rest of this entry »
Biological Design PhD student Rene Daer just successfully defended her thesis “Expanding Applications of Portable Biological Systems: Enhancements to Mammalian Gene Editing and Bacterial Quorum Sensing” today at 3 – 5 pm in Biological Design Auditorium B. Thank you to all of the friends, family, and colleagues who came to show their support.
This day is especially exciting since Dr. Rene Daer will my (Dr. Haynes’) first PhD graduate. On behalf of the Haynes lab, I hope this training experience launches a fun and fruitful career!
Haynes lab members Alyssa Henning, Ben Nyer, and Dr. Karmella Haynes will be presenting research at a 2017 Fall Retreat organized by the Engineering Biology Research Consortium (EBRC). The retreat will take place at Georgia Tech in Atlanta, GA September 22 – 23, 2017. EBRC members include some of the most prestigious labs in synthetic biology. Attendees will come from academic, industry, and government institutions from across the country.